KidsAP started on 1st January 2017, over the next 42 months the consortium will assess the ability of the artificial pancreas to improve glucose control in the most vulnerable population with type 1 diabetes, children aged 1 to 7 years.
The KidsAP project is divided into work packages.
KidsAP will include two clinical studies. This first, KidsAP01 is a pilot study which will compare closed loop insulin delivery using standard strength and diluted insulin. The results of this study will feed into the design of the main study. Half of the children will receive diluted insulin in the closed loop system for three weeks, followed by standard strength insulin for three weeks. The other half of the children will receive standard strength insulin in the closed loop system for three weeks, followed by three weeks of diluted insulin in the closed loop system
The main study, KidsAP02 will compare closed loop intervention over 12 months with either full strength or diluted insulin as determined by the pilot feasibility study KidsAP01, with state of the art Predictive Low Glucose management insulin pump therapy using the standard Medtronic 640G pump.