We hypothesise that closed loop insulin therapy will give increased time in range compared to sensor augmented pump therapy. This study builds upon previous and on-going studies of closed loop systems that have been performed in Cambridge in children and adolescents with type 1 diabetes.
| Design | Open-label, multicentre, multi-national, randomised, 2-period crossover study (n=72 children from 7 sites) |
| Target population | Children aged 1-7yrs with diagnosis of type 1 diabetes for at least 6 months, on insulin pump therapy for 3 or more months, willing to use continuous glucose monitoring and closed loop |
| Chief Investigator | Prof Roman Hovorka, University of Cambridge |
| Principal Investigators | Dr Ajay Thankamony, Addenbrooke’s Hospital
Dr Carine de Beaufort, University of Luxembourg Dr Fiona Campbell, St James’s University Hospital Dr Elke Fröhlich-Reiterer, Medical University of Graz Dr Sabine Hofer, Medical University of Innsbruck Dr Thomas Kapellen, University of Leipzig Dr Birgit Rami-Merhar, Medical University of Vienna |
